Saturday could prove to be a pivotal day in the Premier League in terms of the race to finish in the Champions League places and the relegation battle.
Among the most eye-catching fixtures are Tottenham hosting Brighton & Hove Albion in what will be Roberto De Zerbi's first home game in charge against his former club, and sixth against third as Chelsea welcome Manchester United to Stamford Bridge.
A West London derby also sees Brentford entertain Fulham, while Leeds United welcome Wolverhampton Wanderers and Newcastle United host Bournemouth.
Be sure to check out our expert and best betting tips from Saturday's Premier League action below:
Today's Premier League betting tips and predictions
Newcastle United vs AFC Bournemouth (15:00)

Pressure is starting to build on Eddie Howe at Newcastle United and he badly needs a win when old club AFC Bournemouth come to St James' Park in the Premier League.
Click here to read our full preview for this match
Tip 1: Over 1.5 first-half goals
The first meeting of these sides earlier in the season was a 0-0 draw but they more than made up for that by sharing six goals at St James' Park in the FA Cup.
Based on Bournemouth's display at the Emirates last week, this should be a open game with chances at both ends. Combining BTTS with over 2.5 goals only pays 8/11 with William Hill but there's more value in over 1.5 first-half goals at 23/20 with BetVictor.
Tip 2: Evanilson goal or assist
Evanilson is a great focal point for the Bournemouth attack and the Brazilian's lovely flick set up Alex Scott's winner at the Emirates last weekend. He's 7/5 with Bet365 for a goal or assist and that looks good value.
Tip 3: Over 0.5 fouls for Tonali, Ramsey and Scott
Both teams have energetic midfields who like to press so we could see a few fouls in the engine room. Combining over 0.5 fouls for Sandro Tonali, Alex Scott and Jacob Ramsey pays evens at Bet365.
Tottenham vs Brighton (17:30)

Tottenham Hotspur will be looking to spark their fight for Premier League survival when they host Brighton & Hove Albion on Saturday evening.
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Tip 1: Both Teams to Score & Both Teams to Receive a Card
Backing both teams to score alongside both teams to receive a card will bring about a 4/5 bet builder on bet365 that holds plenty of appeal.
This selection would have paid out in seven of Spurs' last eight Premier League home matches.
The case for siding with this selection is strengthened by the fact that this combination clicked in this season's reverse fixture between the two teams.
Tip 2: Richarlison To Be Fouled 2+ Times
Having been fouled two or more times in three of his last five Premier League appearances, Richarlison looks a solid pick to be brought down at least twice again here at 4/5 with bet365.
Tip 3: Diego Gomez To Be Carded
Diego Gomez has been booked in three of his last four Premier League outings, making a repeat on Saturday evening a value option at 11/4 on PaddyPower.
Chelsea vs Manchester United (20:00)

Two clubs in the hunt for Champions League qualification meet at Stamford Bridge on Saturday night as out-of-form Chelsea host third-placed Manchester United.
Click here to red our full preview for this match
Tip 1: Both Teams to Score & Over 2.5 Goals
Given Chelsea’s poor run of form and Manchester United’s patchy away record, it’s hard to put any trust in either side, and backing goals seems the sensible option.
Manchester United’s ope
ning 16 Premier League encounters on the road this season have averaged 3.25 goals per game, with Both Teams to Score landing in 14 (88%) of them – including in 13 of their past 14 – whilst 12 of their last 15 have also gone Over 2.5 Goals.
What’s more, eight of the Blues’ last 10 Premier League outings have seen a minimum of three strikes – with seven (70%) seeing goals at both ends – and another high-scoring clash looks on the cards at the Bridge on Saturday.
Tip 2: Bruno Fernandes to Score or Assist
Bruno Fernandes took his tally of assists in the Premier League this season to 17 on Monday night, as he set up Casemiro’s goal in their 1-2 loss at home to Leeds United.
The United skipper also has eight goals to his name in the Premier League this campaign – including one in the reverse fixture against the Blues in September – and the 10/11 on offer at bet365 for the Portuguese international to Score or Assist in West London on Saturday appeals to me.
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