Millwall sit just a point above the EFL Championship drop zone after five games but a win in this London derby with Queen's Park Rangers would send them soaring up the table and above the Hoops.
Both these sides finished in the bottom half last term and a similar fate probably awaits them based on how they have started the new campaign.
Millwall have collected just four points so far but boss Neil Harris will take heart from the fact they've conceded just two goals across their last four games in all competitions.
The problem has been scoring, with blanks in three of those matches, but it has been a different story for QPR who have netted in all eight of their games this term.
Keeping their opponents out has been the big issue for gaffer Marti Cifuentes, with his team yet to keep a clean sheet, so it will be fascinating to see how this game pans out.
How the bookies view it: Lions have lost their bite
With Millwall struggling for goals, it's no great surprise to see them as Betano's 11/5 outsiders here. Queen's Park Rangers are 6/5 favourites and the draw pays 21/10.
Recent head to head: Hoops just have the edge
This London derby has been fiercely contested in recent years, with the last 10 meetings producing five QPR wins, three Millwall victories and two draws. Home advantage was key last season, with Millwall winning 2-0 at the Den before QPR won by the same score in the return.
Players to watch: Enter the Frey
Swiss forward Michael Frey has made a good start to the season for Queens Park Rangers, netting three times in six games. He's 12/5 for anytime scorer with Betano in this clash.
I flagged Josh Coburn up as a Millwall threat against Luton but he picked up a first-half injury that could rule him out for a couple of months. Macaulay Langstaff replaced him in that game and is 13/5 to open his account for the season here.
Probable line-ups
Queen's Park Rangers star Ilias Chair looks set to miss out again with the back injury he picked up in pre-season. In addition to Coburn, Millwall look set to be without Mihailo Ivanovic, Jake Cooper and Billy Mitchell.
Queens Park Rangers: Nardi, Dunne, Cook, Field, Paal, Santos, Colback, Dembele, Madsen, Andersen, Frey.
Millwall: Jensen, Hutchinson, Tanganga, Bryan, Leonard, Watmore, Saville, De Norre, Esse, Honeyman, Longstaff.
Anything else catch the eye?
With Millwall lacking punch up front, especially after the injury to Coburn, I'm going to bet against BTTS in this game at 10/11 with William Hill.
This London rivarly isn't quite as fierce as some of the others but it could still be a pretty fiery game with both teams desperate for a win. Bet365 are offering 11/8 on both teams picking up two more cards and that looks worth a punt.
The half-time draw is always a good option in games like this and it pays a decent 21/20 with Bet365 here. Over 10.5 corners also appeals and that's only marginally shorter at 10/11.
This England Championship match between Queen's Park Rangers and Millwall will be played on Sep 21, 2024 and kick off at 12:30. Check below for our tipsters best Queen's Park Rangers vs Millwall prediction. You may also visit our dedicated betting previews section for the most up to date previews.