Hoffenheim will take on RB Leipzig on Saturday, 23 November in a match that will have a big impact on both ends of the Bundesliga table.
The hosts come into the match in 15th position but a defeat on Saturday could see them drop into the relegation zone.
RB Leipzig, meanwhile, are second in the league table but after failing to win their last two matches before the international break, they are at risk of falling too far behind Bayern Munich.
How the bookies view it: Leipzig start as favourites
The international break came at the right time for RB Leipzig and they will be feeling confident ahead of this one. Despite their two poor results prior to the break, they still start as favourites here with Betfred pricing them at 11/10 to get the win. Hoffenheim are the underdogs at 23/10 while the draw has been priced at 13/5.
Recent head-to-head: Advantage Leipzig
RB Leipzig's price of 11/10 looks extremely generous when you consider how good their recent record is against Hoffenheim. Leipzig are unbeaten in their last six matches against Hoffenheim and five of those were victories which bodes well for them ahead of Saturday's clash.
Hoffenheim should take encouragement from the fact they drew 1-1 with RB Leipzig the last time the two sides met at the Rhein-Neckar Arena.
Players to watch: Two stars in need of a goal
The two biggest names on either side are in desperate need of a goal this weekend with Hoffenheim's Andrej Kramaric and RB Leipzig's Benjamin Sesko both in the midst of disappointing runs of form.
Kramaric, who passed the 100-cap mark for Croatia last month, has now gone eight games without a goal or assist for club and country which has led to many people speculating whether he is now over the hill at the age of 33.
Meanwhile, Sesko has failed to live up to the hype so far this season and has largely played in Lois Openda's shadow. The Slovenian has been tipped as a £100m striker in recent years but has scored just one goal in his last seven appearances for Leipzig.
If Leipzig are to remain in the title race and if Hoffenheim are to start climbing the table, both men are going to need to find their shooting boots soon.
Predicted line-ups
Hoffenheim are missing several players including a trio of defenders in Stanley N'Soki, Ozan Kabak and Christopher Lenz. They are also short in midfield with Finn Becker and Grischa Promel in the treatment room. Leipzig are also missing key defenders with David Raum and El Chadaille Bitshiabu out but their biggest loss remains Xavi Simons.
Hoffenheim: Baumann – Kaderabek, Chaves, Akpoguma, Jurasek – Grillitsch, Stach, Bischof – Kramaric, Berisha, Bulter
RB Leipzig: Gulacsi – Geertruida, Klostermann, Orban, Henrichs – Haidara, Baumgartner, Vermeeren, Nusa – Openda, Sesko
Anything else catch the eye?
RB Leipzig play quite an expansive and open style of football which frequently lends itself to the both teams to score market. Four of their last five matches have seen goals go in at both ends and BTTS has been priced at 4/9 by Betfred for Saturday.
This German Bundesliga match between Hoffenheim and RB Leipzig will be played on Nov 23, 2024 and kick off at 14:30. Check below for our tipsters best Hoffenheim vs RB Leipzig prediction. You may also visit our dedicated betting previews section for the most up to date previews.