Udinese v Milan
After Champions League defeat to Liverpool in midweek ended their European interest for the season, Milan's full focus is on Serie A glory.
They hold a one-point lead at the top and are seeking a third straight league win in Saturday's clash with a Udinese side who have Gabriele Cioffi in interim charge for the first time following the sacking of Luca Gotti.
A run of one victory in 13 saw Gotti bulleted with Udinese in 13th place and Cioffi faces a baptism of fire against the table-toppers. Back Milan at 10-11 with Bet365.
Fiorentina v Salernitana
Another Serie A tussle sees Fiorentina bid to strengthen their top-four hopes when they welcome rock-bottom Salernitana.
Sixth-place Viola are a force at home, winning their last four on the bounce, and should be far too strong for the visitors who have taken one point from 18 and already look destined for the drop.
Valencia v Elche
Valencia are on the rise after a sticky spell of seven winless games and aiming to add to local rivals Elche's relegation worries.
Los Che have gone five without defeat while new Elche boss Francisco made a winning debut last weekend as his side beat Cadiz at home for a first victory in eight.
However, they are just three points above the drop zone and a derby trip to the Mestalla is a tough assignment. Valencia can edge this one at 11-14 with SBK.
- Valencia v Elche (5.30pm)
- Udinese v Milan (7.45pm)
- Fiorentina v Salernitana (2pm)
- (36-10, Bet365)