A resurgent Inter Milan will be looking to continue their recent rise up the table as they welcome Spezia for a midweek Serie A fixture. Spezia have relegation worries at the moment and should find things difficult at the home of the champions.
Inter Milan have got their title defence back on track and are unbeaten in their last five Serie A matches. They are now up to third on the table and could move to within one point of leaders Napoli if results go their way this week.
Manager Simone Inzaghi has got his team playing with plenty of confidence with four wins in their last five Serie A matches. They claimed a 2-0 victory at Venezia in their previous fixture with Hakan Calhanoglu and Lautaro Martinez getting the goals.
Home form remains pivotal for Inter Milan, who have now won their last three matches across all competitions at San Siro.
Things are looking a bit bleak for Spezia at the moment as they are plagued by relegation worries. They have claimed just three wins from 14 Serie A matches and are just one point above the bottom three.
There appears to be no respite for Spezia, who travel to Inter Milan with three defeats from their last four Serie A matches. Thiago Motta’s men suffered a 1-0 home defeat to Bologna in their previous fixture.
Spezia also have a poor record on their travels and have lost their last four away matches. Some of their heaviest defeats have come on the road, including a 4-0 loss to Verona while they were also beaten 5-2 by Atalanta in their last away fixture.
How the bookies view it
The bookies have Inter Milan as overwhelming favourites with a home win priced at 21/100 by Unibet. An unlikely victory for Spezia is valued at 16/1 by BetVictor while a draw is set at odds of 13/2 by bet365.
Head to head
Inter Milan were unbeaten against Spezia last season, earning a 2-1 victory at the San Siro before playing out a 1-1 draw in the reverse fixture.
Players to watch
Lautaro Martinez has scored in his last two Serie A matches and will be the one to watch for Inter Milan. The goal against Venezia was his seventh for the season and the Argentine striker could be tipped to get on the score sheet on Wednesday at 5/6 with Betfred.
Inter Milan have looked solid at the back lately and with Spezia unconvincing in attack, they will be targeting a shutout. Milan Skriniar and Alessandro Bastoni have featured in defence in recent weeks and can lead the Nerazzurri to a clean sheet at 11/10 with Paddy Power.
Anything else catch the eye?
Inter Milan have won to nil in their last two matches and could be set for a repeat at 23/20 with BetVictor. Given their defensive record, BTTS NO can also be considered at evens with BetVictor.
Inter Milan can be backed as the only team to score at 21/20 with William Hill while a -2 handicap could also be on the cards at 6/4 with Paddy Power.
This Serie A match between Inter Milan and Spezia will be played on Dec 1, 2021 and kick off at 17:30. Check below for our tipsters best Inter Milan vs Spezia prediction. You may also visit our dedicated betting previews section for the most up to date previews.
In December 2020 we sadly 
Win to nil is ok