Atalanta v Chievo (2pm)
With little left to play for for either of these sides, the players could be forgiven for casting one eye to their summer breaks.
A 2-1 defeat at Udinese condemned Atalanta to a third consecutive loss this month and they can finish no higher than 14th but as low as 17th.
Cyril Théréau scored for the second straight fixture as Chievo were held to a 1-1 draw at home to Torino. Mussi Volanti have lost just one of their last half-dozen matches and a win could see them clinch a top-half finish. With little motivation for either outfit this could be a stalemate from start to finish.
Best Bet: Draw at 3.17
Bologna v Genoa (2pm)
Bologna will be looking to end the season on a high after ending a winless streak with their 2-0 win at Parma last weekend.
They had failed to maximum points from any of their previous eight fixtures and have taken two points from their last four at Stadio Renato Dall'Ara.
Genoa have survived in Serie A by the skin of their teeth but a six-match unbeaten run has shown their battling qualities as the season draws to an end.
Last weekend they held Inter Milan to a goalless draw, although away from home only one side has netted fewer in the league than Davide Ballardini's side. Genoa's away matches have averaged less than two goals per game, and that might be the way to go in this clash.
Best Bet: Under 2.5 goals at 2.16
Cagliari v Lazio (7.45)
A 1-1 draw away at champions Juventus leaves Cagliari down in 12th spot heading into the final game of the campaign. Ivo Pulga's troops are stuttering to the season's end, and are winless in five matches, while scoring once in their last 380 minutes of action.
Lazio have kept their hopes of a European place for next season alive with a 2-0 victory over Sampdoria last weekend keeping them within two points of fifth-placed Udinese. The Biancocelesti have won all of their last three games at an aggregate of 11-1. Still with their eyes on fifth spot, an away victory in this one looks on the cards.
Best Bet: Lazio at 1.67
Inter v Udinese (7.45)
A disastrous season for Andrea Stramaccioni and his Inter Milan side comes to a close on Sunday as they face the prospect of no European football next term for the first time since 2000.
The Nerazzurri are down in ninth having won just one of their last seven and the manager's future is reportedly up for discussion at the climax of the campaign. Udinese, meanwhile, will clinch a Europa League spot with victory here after beating Atalanta 2-1 last weekend.
That was a seventh straight victory for the Zebrette and only a fool would bet against them making it eight on the final day of the season.
Best Bet: Udinese at 2.11
Palermo v Parma (7.45)
Palermo's time in Serie A draws to a close this weekend as they seek to avoid a fourth straight league defeat in May. They fell to a 1-0 loss at Fiorentina last time out confirmed their relegation to the second tier.
Parma finished their home schedule with a 2-0 defeat to Bologna last weekend, although they have had little to play for for a while now. Firmly in mid-table, the Crociati have struggled away all term, with a win at Cagliari a fortnight ago being their only victory on the road in their last eight attempts.
Best Bet: Palermo at 2.22
Pescara v Fiorentina (7.45)
Pescara will be collecting Serie A's “cucchiaio di legno” (wooden spoon) this season after looking out of their depth for the most part.
A 1-0 defeat at Catania last time out was a fourth in a row for the Delfini, and a 16th loss in their last 18 attempts, with the other two only being draws.
Fiorentina are still harbouring Champions League ambitions and a clash with the bottom side presents them with the perfect opportunity to pressurise third-placed AC Milan.
The Viola are two points behind AC going into this one and boast five wins from their last six attempts. They could probably be awarded three points before this one even kicks off.
Best Bet: Both teams not to score at 1.74
Siena v AC Milan (7.45)
Siena are facing the drop into Serie B for next season but will want to give their fans something to celebrate in their final home match and end the five-game losing sequence they're currently on.
They have scored one and conceded 11 in that five-match run, while they're winless in five on home turf.
Given their head-to-head record with Fiorentina, AC Milan know a point might not be enough to secure third spot here so will need to get back to winning ways.
A draw at home to Roma last weekend ended their three-match winning run and they're likely to go for the jugular early on here and seal third sooner rather than later.
Best Bet: Four or more goals at 2.25
Torino v Catania (7.45)
Torino have been on their summer holidays for the last two months judging by their results – they've lost five and drawn three of their last eight Serie A matches.
At home they have lost three of their last four, conceding nine in that time, while scoring just one in their last four anywhere themselves.
Alejandro Gómez's goal was enough for Catania to clinch victory at home to bottom-club Pescara last time out, leaving them with only one defeat in their last seven.
Rolando Maran's side are in eighth spot going into this one and could equal a club record high finish if they of eighth if they better Inter's result which they should do.
Best Bet: Catania at 3.69