EVERTON head for St Mary's confident of adding to home fans' misery after the unpopular decision to axe boss Nigel Adkins.
I don't like backing against sides with new managers but Southampton fans are up in arms, players aren't happy and it's not an ideal situation for Mauricio Pochettino.
The Argentine will have to hit the ground running if he has any chance of winning over the faithful and the squad Adkins built with many of the players accompanying him from League One to the Premier League.
Everton will feel the timing of the game is perfect and they'll be out to bag three points to stay in the hunt for a Champions League place.
They've lost only three times this season and once in nine games and crucially have netted in all but one of their away fixtures.
But Southampton were in good form under Adkins with his sacking seemingly nothing to do with results but personality. The Saints drew 2-2 at Southampton after beating Aston Villa so they're a decent side and the only questions is: How will they play for Pochetti.
Everton have scored in 11 of their last 12 league games and Southampton have been hot at home with the dangerous Rickie Lambert always likely to pitch in with a goal.
If Adkins was still in the dugout I'd be on draw at 13-5 with bet365 and BetVictor and possibly even Saints at 10-3 with Blue Square. But as he's not there I'm going to side with Everton at 21-20 with Ladbrokes, William Hill and Paddy Power.
Marouane Fellaini starred in Everton's 3-1 win against the Saints at Goodison and is 7-1 at BetVictor to bag the opener and 11-5 to net at anytime. Nikica Jelavic bagged a double in that match but has netted just six this season. He is 11-2 at BetVictor to break the deadlock and 13-8 to score again.
Lambert as always is Saints' biggest threat and turned the game his side's way when he came on against Chelsea and scored. Lambert is 8-1 at Paddy Power to bag the opener and 13-5 to score at anytime.
With Fellaini and Jelavic slightly off the boil maybe the guy to consider for first goal is Steven Pienaar who has given the African Nations Cup a bodyswerve. The South African is 12-1 at Ladbrokes and Paddy Power to score first and 5-1 with Coral at anytime.
Over 2.5 goals at Southampton
Pienaar to score
(5-1, Paddy Power)
Lambert to score
(13-5, Paddy Power)