PSG manager Laurent Blanc has accused Edinson Cavani and Ezequiel Lavazzi of showing a “total lack of respect” after returning late from their Christmas holidays.
The pair will sit out a second game in a row, having missed the French Cup midweek win over Montpellier, when the capital side play Bastia on Saturday.
Uruguayan Cavani and Argentine Lavezzi returned to the club last weekend but by that stage had missed a mid-season camp in Morocco and both have been fined and dropped and linked with moves away.
PSG return to action after a difficult week for everyone in the French capital after the terrorist attacks and Blanc held a minute's silence at his press conference on Friday.
Despite losing just one of their opening 19 league matches PSG stand only third in the table after drawing eight matches.
St Etienne, just two points back in fourth place, head to Reims on Saturday, while Lille tackle bottom-of-the-table Caen and Guingamp face Lens.
Rennes boss Philippe Montanier will be looking for his team to end their recent run of poor Ligue 1 form with victory at Evian. Montanier's men have slipped to eighth in the table following a run of three successive defeats but Rennes won 6-2 when the teams played in August.
Ex-Newcastle star Hatem Ben Arfa could make his debut for Nice against Lorient while on Sunday Lyon, who start the weekend in second, play Toulouse who beat them earlier in the season.
Monaco, seeking a fifth straight league win and eighth in all competitions, take on Bordeaux at the Stade Louis II and are a best 4-5 at Betfred.
Nantes play Metz, who lost six out of seven Ligue 1 matches before the Christmas break to tumble towards relegation trouble.