Spanish sides have dominated this tournament winning seven out of 12 and favourites have lifted the trophy in 12 of the last 14 finals.
Atletico are well fancied in the betting at a best 7-10 with bet365 to win in 90 minutes and 4-11 at McBookie on the outrights.
For a final it's a little short but it's easy to see why as Diego Simeone's side are so solid at the back.
They've conceded just 20 goals in La Liga – nine fewer than champions Barcelona – and two in the quarter-finals and semi-finals. Atletico are 11-10 at Paddy Power to keep a clean sheet and 8-5 with Unibet to win to nil.
Marseille's strength lies at the other end – they've kept just three clean sheets in 20 but netted 16 in eight knockout ties with Dimitri Payet running the show.
Two things give Marseille hope – the match being staged in Lyon will give them an advantage as will Simeone's touchline ban.
Marseille are 5-2 at Sky Bet to lift the trophy and 5-1 at Marathonbet to win after 90 minutes.
To have any chance they'll have to keep Antoine Griezmann and Diego Costa quiet. French star Griezmann has netted 27 goals this season and is 17-5 to score first and 11-8 at Unibet to net at any time.
He'd be my first choice but Costa can't be ruled out and is 13-8 at bet365 to score.
Atletico have won three of their last four 1-0 and another pays 21-4 at Unibet.
- Griezmann to score
- Atletico to win to nil