
Plymouth Argyle have already claimed one Premier League scalp in this season's FA Cup and will now look to pull off an even bigger shock when they welcome Liverpool to Home Park in the fourth road.
Nobody gave the Pilgrims a prayer away to Brentford in the last round but the Championship strugglers defended for their lives and grabbed a 1-0 win thanks to a strike from Morgan Whittaker.
That rousing victory failed to turn Plymouth's season around though and they took just two points from their next four league games, while star man Whittaker was sold to Middlesbrough.
A 2-1 win at home to West Brom last weekend lifted spirits a little ahead of this FA Cup clash but Argyle will need to play out of their skins to stand a chance against Liverpool.
Arne Slot's side are red-hot favourites for the Premier League title and remain on track for an unprecedented Quadruple after getting past Spurs in the EFL Cup semi-final on Thursday night.
They have probably been the best team in Europe this season, with Slot's side also leading the betting for Champions League glory, so it would be a massive surprise if they slipped up against a team rooted to the foot of the Championship table.
How the bookies view it: Red-hot favourites
Plymouth Argyle have been written off, with BoyleSports pricing them at 9/1 to go through and a whopping 14/1 for a win in 90 minutes. Liverpool are just 1/25 to reach the fifth round and 2/13 to get the job done without extra time or penalties. The draw at 90 minutes is also big at 13/2.
Head to head: Last Cup clash gives Pilgrims hope
These sides have faced off just twice since the 1960s and both those games came in the FA Cup eight years ago. Plymouth claimed a shock 0-0 draw at Anfield to take it to a replay and Liverpool edged a 1-0 victory at Home Park.
Players to watch: Harvey set to shine
Slot will probably make lots of changes with a quick turnaround after Thursday's clash with Tottenham. Harvey Elliott has netted twice in his last three outings and the 21-year-old looks decent value at 2/1 with BoyleSports for anytime scorer.
Ryan Hardie will be hoping his match-winning double against West Brom off the bench earns him a start for this cup tie. The Scottish striker is 5/1 to follow it up with a famous goal against Liverpool.
Probable line-ups
Liverpool only have Trent Alexander-Arnold and Joe Gomez out through injury but Slot is likely to rest several big hitters.
Plymouth boss Miron Muslic is still missing Joe Edwards, Ben Galloway and Kornel Szucs.
Plymouth Argyle: Hazard, Pleguezuelo, Katic, Talovierov, Houghton. Puchacz, Randell, Sorinola, Wright, Bundu, Hardie.
Liverpool: Kelleher, Bradley, Quansah, Endo, Robertson, Jones, McConnell, Morton, Elliott, Jota, Nunez.
Anything else catch the eye?
Plymouth will probably set up to frustrate and how the game pans on will depend on whether Liverpool can get an early breakthrough. The corner count racked up in that win over Brentford, with the Bees winning 13-3 on that front, so that market might offer the best value.
Over 11.5 match corners looks good at 13/8 with BoyleSports while the same firm are offering 8/5 on Slot's team winning over 8.5 flag kicks.
We could see a few cards as Plymouth try to knock the Reds out of their stride and over 1.5 cards for the Pilgrims appeals at 8/11 with Bet365. Former Rangers stopper Nikola Katic made his debut for Plymouth in the win over West Brom after signing from FC Zurich. He always got stuck in when he was at Gers so could be worth a punt for a card here at 11/2.
This FA Cup match between Plymouth Argyle and Liverpool will be played on Feb 9, 2025 and kick off at 15:00. Check below for our tipsters best Plymouth Argyle vs Liverpool prediction. You may also visit our dedicated betting previews section for the most up to date previews.