Benfica finally got off the mark in this season's UEFA Champions League in the last round of fixtures and will now be looking to bank another three points when Napoli come calling.
A horror loss at home to Qarabag set the tone for Benfica's Euro campaign, with Bruno Lage sacked and replaced by Jose Mourinho.
The self-styled Special One then oversaw losses to Chelsea, Newcastle and Leverkusen but the Eagles came out on top in a must-win clash with Ajax.
They may need to win their final three games to reach the knockout stages and it won't be easy against the Italian champions.
Napoli have banked seven points from their five Champions League games so far and still have a bit of work to do to secure safe passage.
A weekend win over Juventus took them back to the summit in Italy's top flight but they've been poor on the road in Europe, losing both their away games.
Manager Antonio Conte now has a fascinating battle of wits with Mourinho, who is starting to work his magic at Benfica, with just one defeat in their last nine games.
How the bookies view it: Eagles have the edge
This is a tricky one to call but the bookies make Benfica favourites and they're 5/4 with most major firms. Napoli look a bit overpriced at 23/10 with Bet365 and the draw pays the same price at BetVictor.
Head to head: Napoli bossing it
These teams have faced off four times and it's Napoli who have held the upper hand, with three wins and one defeat. They last clashed in the Champions League nine years ago and the Italians came out on top in both games, including a 2-1 victory in Lisbon.
Players to watch: Vangelis on song
Greek striker Vangelis Pavlidis should lead the line again for Benfica and his cool finishing could make the difference. The striker is 7/4 at Paddy Power to add to his 11-goal tally this term.
Rasmus Hojlund heads into this game with his confidence up after a matchwinning double at the weekend. The Dane is 11/4 with Paddy Power to grab another goal in Lisbon, which looks decent value.
Probable line-ups
Mourinho remains without long-term injury absentees Dodi Lukebakio, Bruma and Alexander Bah while Henrique Araujo is a doubt.
The Serie A giants still have some key players out, with Alex Meret, Billy Gilmour, Frank Anguissa, Kevin De Bruyne, Miguel Gutierrez and Romelu Lukaku likely to be on the sidelines again.
Benfica: Trubin, A Silva, Dedic, Dahl, Otamendi, Barrenechea, Aursnes, Sudakov, Barreiro, Rios, Pavlidis.
Napoli: Milinkovic-Savic, Buongiorno, Rrahmani, Olivera, Beukema, McTominay, Di Lorenzo, Lobotka, Neres, Hojlund, Lang.
Anything else catch the eye?
Benfica need a win to keep their Champions League hopes alive so it bodes well for a decent game, especially with Napoli losing 6-2 to PSV on their last road trip in Europe.
I thought BTTS would be shorter than 5/6 with Betway and adding on over 2.5 goals boosts the odds to a decent 11/8 at BOYLE Sports.
Each team should have chances and combining a shot on target for Pavlidis and Napoli midfielder Scott McTominay pays 11/8 at Bet365.
Benfica midfielder Richard Rios has picked up seven yellows this season so he looks worth a punt to go into the book at 5/2 with Paddy Power.
This game could be spicy and over 2.5 Benfica cards looks good at 11/8 with Bet365, who also price a red card at 4/1.
GambleAware