ATLETICO MADRID face a huge challenge when they host Italian champions-elect and Champions League dark horses Inter Milan on Wednesday.
Simone Inzaghi's side are cantering to their 20th Serie A title having built up a lead of 16 points with ten games to go having lost just one league game all season.
It's been a procession and their recent form is outstanding. A 1-0 win away at high-flying Bologna at the weekend was their 13th win in a row in all competitions.
Included in that run was a 1-0 first leg lead in this Round of 16 clash at the San Siro and their success is built on a trademark rock solid Italian-style defence.
They have only conceded six goals away from home in 14 games and are unbeaten too so a trip to the Spanish capital shouldn't faze them.
However, Diego Simeone is a past master at finding a way to win and there will be a raucous atmosphere at the Metropolitan.
Atletico currently sit in fourth place in La Liga and are 14 points languishing behind city rivals Real Madrid. However, they have been excellent at home having won 13 and drawn once so far.
But their inconsistent side was summed up at the weekend when they slumped to a 2-0 defeat at lowly Cadiz.
How the bookies view it
Inter are favourites here at 6/4 with Coral, with Atletico 19/10 outsiders on their own patch with bet365. The draw is 12/5 with 888sport.
Recent head to heads
It took a goal 11 minutes from time from Marko Arnautovic to finally break Atletico's resistance in the first leg in Italy.
Their only other meeting came when Atletico won the European Super Cup 14 years ago,
Players to watch
Alvaro Morata has scored 21 goals this season for Spain and Atletico, but he's only netted one in his last ten games. The 31-year-old is 23/10 to score anytime with Paddy Power.
Argentinian hitman Lautaro Martinez has been in fine form for club and country this season with an excellent return of 26 goals in 41 games. He is 2/1 to score with bet365.
Anything else catch the eye?
This is a tricky one for punters on a number of fronts. Inter are clearly the better team with an outstanding recent record against a toiling Atletico side who have had a season to forget. They are also excellent travellers.
However, Inter don't need to win and for all their troubles, Atletico are very, very stromg at home. They have won their last seven games at home and have already seen off Italian opposition when they beat Lazio.
It points to Inter getting the draw they need to qualify.
Inter would bite your hands off now for a goalless draw and that's far from impossible with their excellent defence. Go for under 1.5 goals at 12/5 at bet365.
This UEFA Champions League match between Atletico Madrid and Inter Milan will be played on Mar 13, 2024 and kick off at 20:00. Check below for our tipsters best Atletico Madrid vs Inter Milan prediction. You may also visit our dedicated betting previews section for the most up to date previews.