Ruud van Nistelrooy takes charge of Leicester City for the first time and will be looking to bank three points against a West Ham United side who continue to look vulnerable.
The new Foxes boss got an idea of the scale of the task on his hands as he watched from the stand at the weekend when Brentford eased to a 4-1 victory over Leicester.
They are still outside of the drop zone but the bookies make Van Nisterlrooy's team second favourites for relegation so the former Manchester United manager has taken on a daunting job.
The King Power will be rocking for his first game though and Leicester will fancy their chances against a Hammers side who lost 5-2 at home to Arsenal on Saturday night.
We flagged up Bukayo Saka as the danger man for the Gunners and Julen Lopetegui's men couldn't cope with him as the winger provided two assists and scored from the spot.
The West Ham boss had eased some of the pressure on him with an excellent win at Newcastle but that rout by Arsenal has cranked up the heat once more and Lopetegui needs a result at the King Power.
How the bookies view it: Hammers the slightest of favourites
With both teams coming off the back of heavy weekend defeats, this is a tough one to call. It's reflected in the odds, with West Ham only marginal favourites at 11/8 with Kwiff. Leicester are 6/4 to start Van Nistelrooy's reign with a win and the draw pays 2/1.
Recent head to head: Nothing in it
This fixture has been keenly contested in recent years, with the last 12 meetings producing four victories apiece and four draws. But Leicester had the upper hand when they last faced off two seasons ago, winning 2-0 in London then 2-1 at the King Power.
Players to watch: Buonanotte a bright spark
Brighton loanee Facundo Buonanotte has impressed this season for Leicester City and his goal at the weekend took his tally to four. The young Argentinian is 29/10 at Kwiff for anytime scorer.
Jarrod Bowen has drawn a blank in his last four games but is still the most reliable of West Ham's forwards. The England international is 37/20 at Kwiff to add to his four-goal tally.
Probable line-ups
Leicester City are still without Harry Winks, Abdul Fatawu, Ricardo Pereira and Jakub Stolarczyk. Crystal Palace loanee Odsonne Edouard didn't even make the bench at the weekend so it will be interesting to see if Van Nistelrooy brings him in from the cold.
West Ham United have star man Mohammed Kudus back after his five-game ban and Lopetegui has to to decide if he's going throw him straight back in. German striker Niclas Fullkrug still isn't ready to return.
Leicester City: Hermansen, Justin, Faes, Vestergaard, Kristiansen, Ndidi, Soumare, Decordova-Reid, Buonanotte, Ayew, Vardy
West Ham United: Fabianski, Todibo, Kilman, Wan-Bissaka, Emerson, Soler, Kudus, Paqueta, Bowen, Soucek, Antonio.
Anything else catch the eye?
With both these sides leaking a lot of goals at the weekend this should be a decent watch. The bookies certainly think so with BTTS just 11/20 at Kwiff and over 2.5 goals also short at 17/25. Van Nistelrooy's arrival could give the Foxes a lift and backing over 1.5 home goals offers better odds at 23/20.
Both managers are desperate for a result so this could be a tasty game with a few cards. The bookies haven't priced up that market yet but try going for a high number of booking points.
Neither team has been winning a lot of corners in recent games so there could be a bit of value in backing under 10 flag kicks at 5/4 with Bet365.
This English Premier League match between Leicester City and West Ham United will be played on Dec 3, 2024 and kick off at 20:15. Check below for our tipsters best Leicester City vs West Ham United prediction. You may also visit our dedicated betting previews section for the most up to date previews.