
Viktoria Plzen have a mountain to climb in their Europa League last-16 clash with Lazio after the Serie A side snatched a stunning 2-1 win with nine men in the Czech Republic last week.
Marco Baroni would have been delighted to get out of Plzen on level terms after having Nicolo Rovella and Samuel Gigot sent off in the final 15 minutes but instead Gustav Isaksen smashed home a winner right at the death.
I was delighted, having backed BTTS and no draw, and the battling win underlined Lazio's status as potential contenders to lift the trophy in Bilbao come May.
They weren't among the favourites earlier in the competition but now sit second in the odds at 11/2 behind Spurs.
Winning at the Stadio Olimpico is a tall order for Plzen but the Czechs will take heart from their first-leg display and face a Lazio side who will have two stars suspended.
How the bookies view it: Czech mate already
Isaksen's late goal last week has made a tough task even harder for Plzen and BoyleSports price them at 12/1 to reach the quarter-finals, with Lazio 1/40 in the same market.
For a win on the night, Baroni's men are 1/3 favourites, with the Czechs at 13/2 and the draw paying 7/2.
Head to head: Second helpings
That clash last Thursday was the first meeting of these sides in Europe. Lazio have now won three of their seven games against Czech opposition, with two draws and two defeats.
Players to watch: Gustav back for more
Isaken's stunning strike in the first leg took the Danish midfielder's tally for the season to five. He will fancy another goal in the return and is 9/4 with BoyleSports for anytime scorer.
Matej Vydra is a familiar face for British fans, having spent most of his career in England with the likes of Derby, West Brom and Watford. The 32-year is now back home and the forward is 11/2 to take his tally for the season to eight goals.
Probable line-ups
Baroni has a selection headache with Rovella and Gigot suspended after those first-leg red cards. Lazio are also set to be without Taty Castellanos, Elseid Hysaj and Fisayo Dele-Bashiru due to injury.
Viktoria Plzen boss Miroslav Koubek has a pretty healthy squad to chose from, with just Cheick Oumar Souare and Christophe Kabongo out injured.
Lazio: Provedel, Patric, Romagnoli, N Tavares, Marusic, Lazarri, Guendouzi, Pedro, Isaksen, Dia, Noslin.
Viktoria Plzen: Jedlicka, Markovic, Jemelka, Dweh, Cerv, Cadu, Kalvac, Vydra, Durosinmi, Sulc, Memic.
Anything else catch the eye?
Viktoria Plzen need to score to keep their hopes alive so this should be a decent game with chances at both ends. BTTS looks decent value at 21/20 with BoyleSports, given the Czechs have scored in 13 of their 15 European games this season.
Adding over 2.5 goals to BTTS boosts the odds to 8/5 while backing Lazio to score in both halves also appeals at 6/5 with BoyleSports.
There could be some bad blood in this tie after five yellows were dished out in addition to those two red cards last week in Plzen.
That makes over 4.5 cards appealing at 5/6 with Bet365 while Plzen midfielder Lukas Cerv is 3/1 with the same firm to pick up a card after being booked in the first leg.
This UEFA Europa League match between Lazio and Viktoria Plzen will be played on and kick off at 17:45. Check below for our tipsters best Lazio vs Viktoria Plzen prediction. You may also visit our dedicated betting previews section for the most up to date previews.