A four-goal lead after the first leg puts Atletico Madrid in pole position for their first Copa del Rey final in nearly 15 years, but they should not underestimate Barcelona, who have been in exceptional form at home throughout the season.
Hansi Flick was adamant that his team is capable of turning things around, and looking at their home form, it is certainly possible.
Barcelona have won every home game in every competition except one (1-2, PSG). In 12 of their 16 wins, they have scored at least three goals, including four against Villarreal over the weekend.
And last year, they managed to score four against Atlético in a match at the same stage of the Copa Del Rey.
Atletico Madrid are in excellent form with three consecutive wins and a decent away record since December – only one loss in their last 10 away games.
They have only five wins, but after the first leg they don't even need to win this match, and we are all familiar with Diego Simeone's style and how good he is in these situations.
Barcelona's chances would be higher against any other team in the world, but Atletico Madrid's style of play makes the task extremely difficult.
How the bookies view it: A home win is inevitable
Bookmakers certainly don't expect anything other than a home win, but there is still plenty of value in the odds, even if you want to pick a straight win for Barcelona.
They are currently available at 1/2, while Atlético Madrid and the draw are roughly equally priced at around 4/1.
Recent head-to-head: Atletico won last time, but Barca have the long-term edge
Matches between Barcelona and Atletico Madrid are always a footballing feast and rarely disappoint in terms of goals.
Four of the last five encounters have featured at least four goals, with Barcelona winning three of them, including the first La Liga match of the season (3-1).
Players to watch: No better time for Torres to wake up than this game
We have two ideas for this matchup. The riskier option is Ferran Torres, mainly because he is currently far from the form he was in at the start of the season. The 26-year-old Spaniard has 16 goals for Barcelona in all competitions, but none in his last six games.
It should be noted, however, that he has scored in three of the last six games against Atletico.
The other option, of course, is Lamine Yamal. The 18-year-old super talent will be highly motivated after his hat-trick against Villarreal at the weekend. He is a great option for both goals and assists with his 18 goals and 14 assists this season.
Backed a player to find the net? Check our Goalscorer Betting guide to see how the markets work and where to find value.
Probable line-ups
Barcelona: Garcia, Balde, Martin, Cubarsi, Kounde, Olmo, Pedri, Raphinha, Lopez, Yamal, Torres
Atletico Madrid: Musso, Molina, Pubill, Hancko, Ruggeri, Lookman, Llorente, Koke, Simeone, Alvarez, Sorloth
Anything else catch the eye?
Barcelona will certainly control the game from the first to the last minute and will throw themselves blindly into attack because they have no other choice.
We certainly expect them to win, and we expect them to do so by scoring several goals, but the tactics we expect may leave them vulnerable to counterattacks, which could lead to a goal for Atletico that would end it all.
It is also possible that Diego Simeone will motivate his team to play a defensive masterclass and shut Barcelona out completely with uninspiring football. However, we prefer to bet on goals and a home win, even though we do not expect Barcelona to qualify.
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