Manchester United and Bournemouth will face off in an all-Premier League affair at Soldier Field in the early hours of Thursday morning.
The two teams are participating in the Premier League Summer Series – a pre-season tournament that is taking place in the USA.
Manchester United hit the ground running in the exhibition event with a narrow 2-1 win over West Ham at MetLife Stadium on Sunday.
That was the Red Devils' first victory of pre-season, with Ruben Amorim’s side playing out a 0-0 draw with Leeds in Stockholm earlier this month.
As for Bournemouth, they also have three points on the board after earning a convincing 3-0 win over Everton at Mercedes-Benz Stadium.
The Cherries have now won each of their three friendly fixtures this summer, so they will be keen to keep the feelgood factor flowing when they face Man United this midweek.
How the bookies view it: Red Devils to deliver
The bookmakers believe that Manchester United will make it two wins from two in the Premier League Summer Series, with the Red Devils odds-on 10/11 favourites on Boylesports.
Bournemouth look overpriced to triumph here at 2/1 with Boylesports while the draw is trading at 23/10 with the same firm. Alternatively, the Cherries can be backed at an eye-catching even-money (1/1) with a +0.25 start on the Asian Handicap.
Head to head: Red Devils rule the roost
Manchester United have claimed top honours from 14 of the overall 24 meetings between the pair, while Bournemouth have five wins to their name, with the other five meetings ending all square. However, it is worth noting that the Cherries have avoided defeat in each of their last four showdowns with United.
Players to watch: Bruno to land a blow?
After scoring both of Man United’s two goals in their weekend win over West Ham, Bruno Fernandes stands out for an anytime strike here at 15/8 on Betfred.
Dango Ouattara bagged one of Bournemouth's three goals against Everton last time out, making him worthy of consideration to make the net bulge again here at 16/5 with Betfred.
Predicted line-ups
Manchester United will once again be without injured defender Lisandro Martinez, while new signing Bryan Mbeumo is not expected to make his debut this midweek.
Bournemouth boss Andoni Iraola has a relatively clean bill of health at the moment, with Enes Unal and Ryan Christie the only two players ruled out through injury.
Manchester United: Bayindir; Yoro, Maguire, Heaven; Dalot, Casemiro, Mount, Shaw; Fernandes, Hojlund, Cunha
Bournemouth: Petrovic; Araujo, Zabarnyi, Senesi, Truffert; Billing, Scott, Brooks; Semenyo, Evanilson, Ouattara
Anything else catch the eye?
Bournemouth look great value to score two or more goals during this contest at 8/5 with Boylesports.
Iraola’s side should come into this clash in confident mood following their aforementioned 3-0 win over Everton.
What's more, the Cherries have netted two or more goals in three of their last four meetings with the Red Devils, striking three times in two of those contests.
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