BARCELONA have already won Group F and Inter are bidding to join them in the last 16 tonight.
Antonio Conte's side – level on points with Borussia Dortmund and boasting a better head-to-head record – know a win will guarantee progress.
Their cause is helped by the fact Barca only have pride at stake and a tough La Liga assignment away to Real Sociedad looming on Saturday.
The Spanish champions are expected to make wholesale changes – Lionel Messi and Gerard Pique have been given the night off and Sergio Busquets, a booking away from missing the first game in the knockout round, also won't feature.
That explains why Inter are as short as 8-15 for the win against the Catalan giants, with a draw chalked up at 19-5 by Unibet, who make Barca 9-2 outsiders.
Barca are on a five-match winning streak since a surprise 0-0 draw at home to Slavia Prague on matchday four and even a much-changed line-up sent out by Ernesto Valverde is set to feature world-class talents such as Frenkie de Jong and Antoine Griezmann.
However, Inter have the incentive and the quality to get the job done. The scoreless stalemate at home to Roma on Friday night was their first dropped points in Serie in six matches and extended their lead at the top to two points over Juventus.
It was also the first time Conte's team have failed to net this season but lightning is unlikely to strike twice, especially with Romelu Lukaku and Lautro Martinez around.
The strike pair have 24 goals between them and combined to devastating effect in the 3-1 win at Slavia Prague on matchday five that kept Inter's qualification hopes alive.
They can help power the hosts through and contribute to a home win and over 1.5 goals at 17-20 with Betway. Unsurprsingly, the duo are favourites in the scoring market, with Lukaku 11-10 and Betfred and Martinez 6-5.
Having scored in four consecutive Champions League games, I'm plumping for Argentina international Martinez to make it five in a row.
For a higher-price punt, try Marcelo Brozovic to be carded at 23-10 with Betfair. The combative Croat midfielder has been booked in three of his last five appearances at the San Siro and will be out to disrupt the visitors' flow.
This UEFA Champions League match between Inter Milan and Barcelona will be played on Dec 10, 2019 and kick off at 20:00. Check below for our tipsters best Inter Milan vs Barcelona prediction. You may also visit our dedicated betting previews section for the most up to date previews.
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