Argentina have breezed through World Cup qualification and will finish top of the pile in South America regardless of how this dead rubber with Ecuador pans out.
After 17 games of the marathon that is CONMEBOL qualifying, Argentina sit 10 points clear of second-place Brazil, having won 12 of their games so far.
The latest was a 3-0 triumph over Venezuela last week and it was an emotional occasion as Lionel Messi scored twice in what looks like being his final game on Argentinian soil.
The 38-year-old has yet to decide if he'll have another crack at glory in next summer's World Cup but the holders look in decent shape even if he decides to give the finals a miss.
Ecuador are also ticking along nicely and have qualified with a bit to spare after losing just two of their 17 qualifiers.
They drew 0-0 in Paraguay in their last outing and that was the eighth stalemate they've been involved in during qualification. With nothing to play for in this final match, it wouldn't be a great surprise if the scores ended level again.
How the bookies view it: Argentina have the edge
With nothing to play for, the bookies are being a bit cagey with their odds for this one. Argentina are still favourites at 6/4 with BoyleSports, who price Ecuador at 12/5 and the draw at 7/4.
Recent head to head: Eight's not great for Ecuador
Argentina are unbeaten in their last eight games with Ecuador but it has been close in the last four meetings, with two 1-0 wins and two 1-1 draws. They last faced off in the 2024 Copa America, with the Argentines edging a win on penalties after a stalemate.
Players to watch: Martinez an able deputy
Messi has been given the night off after such an emotional night against Venezuela. Inter Milan star Lautaro Martinez should get the nod to start up front and he's 9/4 at Bet365 for anytime scorer.
Ecuador boss Sebastian Beccacece may go with a strong side as it's a good chance to claim the scalp of the world champions. Enner Valencia is usually a threat and the veteran is 2/1 to add to his tally of 46 international goals.
Probable line-ups
Beccacece fielded a youthful line-up against Paraguay but experienced campaigners such as Moises Caicedo and Alan Franco are set to return in this one.
Messi misses out for Argentina and boss Lionel Scaloni might be tempted to give a few fringe players a run-out.
Ecuador: H Galindez, Hincapie, Ordonez, Pacho, Estupinan, Vite, Castillo, Franco, Caicedo, Valencia, Angulo.
Argentina: Martinez, Montiel, Tagliafico, Balerdi, Otamendi, Lo Celso, De Paul, Simeone, Gonzalez, Martinez, Alvarez.
Anything else catch the eye?
With nothing to play for, this match could easily fizzle out and the bookies think it will dull, with under 2.5 goals just 4/9 at BoyleSports.
The half-time stalemate is another good option but the odds aren't great for that either as it pays only 4/5.
It's usually fiery whenever two South American teams face off but this match should lack the normal intensity. That makes under 3.5 cards worth considering at evens with Bet365.
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