WAYNE ROONEY'S out for Man United, Aston Villa's Christian Benteke is of course out for the season but who else is missing this weekend?
Here's team news from some games in England and Scotland that might help you make your picks.
Aston Villa (12) v Fulham (20)
Paul Lambert faces a striker crisis with Christian Benteke expected to be sidelined for up to six months after suffering a serious Achilles tendon injury in training on Friday, while Gabby Agbonlahor is battling to recover from a sickness bug. Nathan Baker has recovered from a foot injury while Karim El Ahmadi is also set to return to contention after a thigh strain.
Fulham midfielder Scott Parker could return from a knee problem but striker Kostas Mitroglou continues to be sidelined by a knee problem. Defender Fernando Amorebieta returns from suspension after being sent off in the 5-0 defeat by Manchester City.
Cardiff (18) v Crystal Palace (16)
Ole Gunnar Solskjaer will have Craig Noone available after the winger missed the last three games because of a groin injury. The manager could start with the side that drew 3-3 at West Brom last weekend, although Noone and loan signing Wilfried Zaha – who impressed off the bench at The Hawthorns – will push strongly for inclusion.
Tony Pulis is hoping to have Marouane Chamakh available for selection after he returned to training earlier in the week following four games out with a hamstring problem. Fellow striker Dwight Gayle (ankle) is unlikely to return in time but Pulis has no other injury concerns.
Chelsea (2) v Stoke (10)
Striker Samuel Eto'o remains out for Chelsea with a hamstring injury but Ashley Cole is back from a knee problem, while Nemanja Matic and Mohamed Salah are available again after being ineligible to face Paris St Germain on Wednesday. Ramires serves the final game of his three-match domestic suspension.
Jonathan Walters returns from suspension for the in-form Potters while on-loan Liverpool winger Oussama Assaidi is close to returning from a knee injury but is not yet back in contention. Defender Robert Huth is out for the rest of the season with his knee injury.
Hull (14) v Swansea (13)
George Boyd is back for Hull after serving a three-game suspension for being found guilty of spitting at Manchester City's Joe Hart – Hull still deny he intended to do so. Goalkeeper Allan McGregor is still in hospital after suffering a bruised kidney and broken ribs against West Ham and Steve Harper will continue in his place.
Garry Monk is set to select from strength after reporting no fresh injury concerns as the Swans look to make it three games unbeaten following a draw against Arsenal and a resounding 3-0 home win against Norwich last time out.
Man City (3) v Southampton (8)
Manchester City are again without top scorer Sergio Aguero although the Argentina striker is back in training after four games out with a hamstring injury. Centre-back Matija Nastasic, who has been out for two months with a knee problem, also remains on the sidelines.
Victor Wanyama will be assessed before Southampton's trip to the Eithad. The Kenyan midfielder has been absent for nearly a month with a leg injury but could return, while Nathaniel Clyne (groin), Kelvin Davis (hip) and Maya Yoshida (knee) will all miss out.
Newcastle (9) v Man Utd (7)
Moussa Sissoko (hamstring) is facing up to three weeks on the sidelines as manager Alan Pardew contends with a worsening injury crisis. The Frenchman will join goalkeeper Tim Krul (shoulder), full-back Mathieu Debuchy (groin), midfielder Sammy Ameobi (knee) and striker Loic Remy (calf) on the casualty list.
Centre-backs Chris Smalling (hamstring) and Jonny Evans (calf) have returned to training and are available for the departing champions but full-back Rafael (thigh) and midfielder Ryan Giggs (hamstring) are doubts. Left-back Alex Buttner (hamstring) is available while Juan Mata and Patrice Evra return after sitting out the 1-1 draw with Bayern Munich. Strikers Wayne Rooney and Robin van Persie (knee) are also missing.
Norwich (15) v West Brom (17)
Norwich defender Joseph Yobo (calf) will be assessed ahead of the clash at Carrow Road while centre-half Michael Turner is back in contention following recovery from a hamstring injury. Winger Elliott Bennett continues his rehabilitation from a long-term knee injury while midfielder Leroy Fer (hamstring) is also still not match fit.
Pepe Mel is set to name forward Saido Berahino in his squad despite the dressing-room fracas that marred last weekend's draw with Cardiff. Defender Jonas Olsson, striker Victor Anichebe, midfielder Claudio Yacob and full-back Billy Jones are all back in contention meaning captain Chris Brunt (knee) is the only absentee.
Dundee Utd (4) v Celtic (1)
Dundee United welcome back striker Nadir Ciftci and left-back Andrew Robertson after the pair missed last weekend's 1-1 draw with Aberdeen through suspension. On-loan Newcastle defender Curtis Good is still out with a hip injury, while defender Callum Butcher is struggling with a leg knock.
Neil Lennon will be without several first-team players again with defender Adam Matthews and utility player Charlie Mulgrew (both hamstring) still sidelined while right-back Darnell Fisher is out with a knee injury. Midfielder Nir Biton and wide man James Forrest (both groin) remain on the sidelines along with winger Derk Boerrigter, who has an abdomen problem.
Kilmarnock (8) v St Johnstone (6)
Suspended Kilmarnock captain Manuel Pascali will complete his two-match ban but Rory McKenzie could feature despite being stretchered off with a shoulder injury after scoring the equaliser in last week's 2-1 win at Motherwell. Greg Kiltie (ankle) is definitely out, as are long-term absentees Darren Barr (hip) and Sammy Clingan (knee).
Gary McDonald will miss the match at Rugby Park with a knee injury but boss Tommy Wright will be able to call upon Lee Croft after he shook off a slight knock picked up in training. Long-term absentees Tam Scobbie (ankle) and Murray Davidson (knee) are out for the season.
Partick (10) v Hearts (12)
Partick forward Kallum Higginbotham will return from suspension but Alan Archibald is struggling to make up the numbers at the back. Conrad Balatoni is kept out with a hand injury, while Aaron Muirhead is at least a fortnight away from his return after undergoing knee surgery on Thursday. Isaac Osbourne (ankle) and Sean Welsh (groin) also remain on the sidelines.
Gary Locke could welcome back derby hero Dale Carrick after the midfielder recovered from a dead leg. Paul McCallum is a doubt through illness, while Jamie Walker may feature for the first time since mid-January, despite being short of full fitness after a foot injury. Long-term absentee Callum Tapping (knee) is definitely out.
St Mirren (11) v Motherwell (3)
Goalkeeper Marian Kello remains on the sidelines as he is still carrying a groin injury and replacement Chris Dilo will again take over in goal. Buddies manager Danny Lennon has no other injury worries.
Motherwell could be without eight players as they prepare to carry out three fitness tests. Craig Reid (toe) and Henri Anier (ankle) are both doubts along with an unnamed player. Stuart Carswell (knee) will miss out while James McFadden (hamstring), Lee Hollis (broken finger), Simon Ramsden (knee) and Paul Lawson (Achilles) also remain on the sidelines.
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